CLINICS

Clinics (Sao Paulo). 2017 April; 72(4): 218-223.
doi:10.6061/clinics/2017(04)05

Copyright © 2017 CLINICS

Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report

Maria de Fátima Borges I * , Beatriz Hallal Jorge Lara I , Janaíne Machado Tomé I , Leopoldo Prezia de Araújo II , Flávio Cesar Lucas Bugiga I , Júlio Cláudio Sousa III , Jacqueline Mendes Fonseca Soares I , Roberto Alexandre Dezena II , Beatriz Pires Ferreira I

Divisão de Endocrinologia e Metabolismo, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR

Divisão de Neurocirurgia, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR

Divisão de Otorrinolaringologia, Universidade Federal do Triângulo Mineiro, Uberaba, MG, BR

*Corresponding author. E-mail: borgmf@uol.com.br

received November 4, 2016; revised December 20, 2016; accepted January 12, 2017.

Abstract

OBJECTIVE:

To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro.

METHODS:

Cross-sectional and retrospective study of thirty cases treated over a period of two decades.

RESULTS:

17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years were analyzed. Twenty-one patients underwent transphenoidal surgery, whichwas associated with somatostatin receptor ligands in 11 patients (39.3%), somatostatin receptor ligands + radiotherapyin 5 patients (17.8%), radiotherapy in 3 patients (10.7%), and radiotherapy + somatostatin receptorligands + cabergoline in 1 patient (3.6%). Additionally, 2 patients underwent radiotherapy and surgeryalone. Six patients received somatostatin receptor ligands before surgery, and 2 were not treated due to refusal and death. Nine patients have died, and 20 are being followed; 13 (65%) have growth hormonelevels o1 ng/mL, and 11 have normal insulin-like growth factor 1 levels.

CONCLUSION:

The current treatment options enable patients seen in regional reference centers to achieve strict control parameters, which allows them to be treated close to their homes.

Keywords: Acromegaly, Gigantism, Treatment, Outcome


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