CLINICS

Clinics (Sao Paulo). 2017 April; 72(4): 224-230.
doi:10.6061/clinics/2017(04)06

Copyright © 2017 CLINICS

Insulin resistance and associated factors: a cross-sectional study of bank employees

Luciane Bresciani Salaroli I * , Monica Cattafesta II , Maria del Carmen Bisi Molina I , Eliana Zandonade III , Nazaré Souza Bissoli IV

Programa de Pós Graduação em Saúde Coletiva, Programa de Pós Graduação em Nutrição e Saúde, Departamento de Educação Integrada em Saúde, Universidade Federal do Espírito Santo, Vitória, ES, BR

Programa de Pós Graduação em Nutrição e Saúde, Universidade Federal do Espírito Santo, Vitória, ES, BR

Programa de Pós Graduação em Saúde Coletiva, Universidade Federal do Espírito Santo, Vitória, ES, BR

Programa de Pós Graduação em Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, ES, BR

*Corresponding author. E-mail: luciane.bresciani@gmail.com

received August 31, 2016; revised November 27, 2016; accepted February 14, 2017.

Abstract

OBJECTIVE:

Insulin resistance is characterized by the failure of target cells to respond to normal levels of circulating insulin, and this condition is related to cardiovascular disease. This study sought to evaluate the prevalence of insulin resistance and its association with markers of metabolic abnormalities and metabolic syndrome in bank employees.

METHODS:

A cross-sectional study was performed on 498 working men and women aged ≥20 years old. The Homeostasis Model Assessment (HOMA-IR) was used to determine the presence of insulin resistance based on cut-off values of ≤2.71 for normal insulin levels and >2.71 for insulin resistance, as established for the adult Brazilian population.

RESULTS:

It was observed that the 52 (10.4%) overweight individuals with insulin resistance were 4.97 times (95%CI 1.31-18.83) more likely to have high HOMA-IR values than the normal-weight participants; among those who were obese, the likelihood increased to 17.87 (95%CI 4.36-73.21). Individuals with large waist circumferences were 3.27 times (95%CI 1.03-10.38) more likely to develop insulin resistance than those who were within normal parameters. The HOMA-IR values differed between subjects with and without metabolic syndrome, with values of 2.83±2.5 and 1.10±0.81 (p=0.001), respectively. The levels of insulin, ultrasensitive C-reactive protein and uric acid were also associated with insulin resistance.

CONCLUSION:

The prevalence of insulin resistance among bank employees is high, and insulin resistance is associated with and serves as a marker of metabolic syndrome. Cardiovascular disease and metabolic syndrome-associated metabolic abnormalities were observed, and insulin resistance may be a risk factor in this group of professionals.

Keywords: Insulin Resistance, Bank Employees, Metabolic Syndrome


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