Clinics (Sao Paulo). 2017 September; 72(9): 547-553.

Copyright © 2017 CLINICS

Early menarche and teenager pregnancy as risk factors for morbid obesity among reproductive-age women: A case-control study

Amanda Gonçalves Neves I , Karina Tamy Kasawara I , Ana Carolina Godoy-Miranda I , Flávio Hideki Oshika I , Elinton Adami Chaim II , Fernanda Garanhani Surita I *

Departamento de Tocoginecologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas – UNICAMP, Campinas, SP, BR

Departamento de Cirurgia, Faculdade de Medicina, Universidade de Campinas, Campinas, SP, BR

*Corresponding author. E-mail:

received February 1, 2017; revised May 7, 2017; accepted June 30, 2017.



The aim of this study was to evaluate potential risk factors, including non-communicable diseases, for morbid obesity in women between 20 and 49 years of age.


We performed a case-control study with 110 morbidly obese women and 110 women with adequate weight who were matched by age and with a 1:1 case to control ratio. All women were between 20 to 49 years old and non-menopausal. Possible risk factors were evaluated through a self-report questionnaire assessing socio-demographic, obstetric and gynecological characteristics, presence of non-communicable diseases and habits. Multiple logistic regression was used to estimate the odds ratio with respective confidence intervals.


Menarche under 12 years old, teenage pregnancy and lower educational level were shown to be risk factors for morbid obesity among women of reproductive age. Incidences of non-communicable diseases (diabetes, hypertension, dyslipidemia, liver disease, lung disease, thyroid dysfunction, and joint pain) were increased in women with morbid obesity.


Early menarche, teenage pregnancy and low education level are risk factors for the occurrence of morbid obesity in women of reproductive age. Some non-communicable diseases were already more prevalent in women with morbid obesity even before 50 years of age.

Keywords: Women’s Health, Morbid Obesity, Reproductive Factors, Non-communicable Diseases, Pregnancy in Adolescence

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